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Genomics

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Summit Helps Veterans Affairs Connect Genetic Dots

To conduct a groundbreaking study of genetic data from more than half a million U.S. veterans, scientists needed tools of the kind found only at the Department of Energy’s Oak Ridge National Laboratory. "This particular study is probably the crown jewel of the field so far," said Ravi Madduri, a…
Matt Lakin
December 18, 2024
DNA researchFeaturedScience

Bigger, Faster, Smarter Genetics Research

A team of researchers used the Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory and a new methodology for conducting a genome-wide association study, or GWAS, to earn a finalist nomination for the Association for Computing Machinery’s 2024 Gordon Bell Prize for outstanding achievement in high-performance computing,…
Coury Turczyn
November 1, 2024
ScienceTechnology

Solving the Protein Puzzle

A simple scoop of soil or water can hold an entire ecosystem–potentially millions or more microscopic organisms and the countless proteins they rely on to survive. Computations performed at the U.S. Department of Energy’s Oak Ridge National Laboratory could help count, sort and catalog each of those proteins in record…
Matt Lakin
October 28, 2022
Science

A New Method for Unraveling Complex Gene Interactions

The first step for biologists who want to develop new, more efficient biofuels is to understand the genetic underpinnings of plants that can be digested by microbes into chemical compounds. One species in particular, the black cottonwood tree, or Populus trichocarpa (poplar tree), has long been a focus of scientists…
Will Wells
May 18, 2020
Science

AI for Plant Breeding in an Ever-Changing Climate

How might artificial intelligence (AI) impact agriculture, the food industry, and the field of bioengineering? Dan Jacobson, a research and development staff member in the Biosciences Division at the US Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL), has a few ideas. For the past 5 years, Jacobson and…
Rachel McDowell
November 13, 2019
Science

Oak Ridge, Lawrence Berkeley National Labs Share 2018 ACM Gordon Bell Prize

Two US Department of Energy (DOE) National Laboratories were recently awarded the 2018 Association for Computing Machinery’s (ACM’s) Gordon Bell Prize for work done on the Oak Ridge Leadership Computing Facility’s (OLCF’s) Summit supercomputer, the most powerful system in the world. The annual Gordon Bell Prize recognizes outstanding achievement in…
Katie Bethea
November 20, 2018
Science

Computing Genes to Support Living Clean

ORNL computational systems biologist Dan Jacobson, left, and OLCF computational scientist Wayne Joubert are part of a team that was named a finalist for the 2018 Gordon Bell Prize for its work to advance genomic science on the Summit supercomputer. This article is part of a series covering the finalists…
Jonathan Hines
October 15, 2018
Technology

Genomics Code Exceeds Exaops on Summit Supercomputer

Researchers at the US Department of Energy’s Oak Ridge National Laboratory broke the exascale barrier, achieving a peak throughput of 1.88 exaops—faster than any previously reported science application—while analyzing genomic data on the recently launched Summit supercomputer. The ORNL team achieved the feat, the equivalent to carrying out nearly 2…
Jonathan Hines
June 8, 2018