Predicting Protein Targets and the Molecules that Bind with Them

Technology

Predicting Protein Targets and the Molecules that Bind with Them

When the COVID-19 pandemic brought the world to a standstill in 2020, pharmaceutical companies countered with remarkable speed to develop mRNA vaccines by the end of that year. Creating new antiviral drugs to treat those who became infected by the deadly coronavirus took about another year of work—astoundingly quick compared…

Coury TurczynNovember 14, 2022

Science

Researchers Pinpoint How Copper Folds Protein into Precursors of Parkinson’s Plaques

Calculations on the Jaguar supercomputer reveal metal binding likely to misfold alpha-synuclein Alpha-synuclein, a protein that misfolds in Parkinson's disease, is shown in its free state (top) and bound to copper (bottom). Copper binding, detailed in the boxed area, accelerates the protein's misfolding. Image credit: Frisco Rose, Miroslav Hodak, and…

OLCF Staff WriterJune 14, 2011

Protein Folding