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Parkinson’s Disease

June 14, 2011

Researchers Pinpoint How Copper Folds Protein into Precursors of Parkinson’s Plaques

Calculations on the Jaguar supercomputer reveal metal binding likely to misfold alpha-synuclein Aided by the Jaguar supercomputer at Oak Ridge National Laboratory (ORNL), researchers at North Carolina State University have figured out how copper induces misfolding in the protein associated with Parkinson’s disease, leading to creation of the fibrillar plaques…